• Non-contact Ultrasonic Crushing Processor
  • LAWSON21-1200
  • LAWSON21-1200
  • Non-contact Ultrasonic Crushing Processor
  • Standard sample processing volume includes 20 holes of 5ml, 15 holes of 10-15ml, and 1 hole of 500-1000ml flask.
Non-contact Ultrasonic Crusher Processor LAWSON21-1200 adopts an isothermal and non-contact method to crush, homogenize, and mix samples, which is suitable for sterile, ultra-microscale and high-capacity crushing. Non-contact ultrasonics are used to disrupt samples through containers. For laboratories that process multiple samples per day or valuable samples, it has the advantages of high-throughput processing, low sample loss, and no cross-contamination.
Product Introduction
Non-contact Ultrasonic Crusher LAWSON21-1200 adopts an isothermal and non-contact method to crush, homogenize, and mix samples, which is suitable for sterile, ultra-microscale and high-capacity crushing. Non-contact ultrasonics are used to disrupt samples through containers. For laboratories that process multiple samples per day or valuable samples, it has the advantages of high-throughput processing, low sample loss, and no cross-contamination.


Working principle:
Non-Contact Ultrasonic Crusher adopts a design that installs the ultrasonic generator at the bottom of the water tank. In traditional probe-type ultrasonic cell disruptors, the microfluidic phenomenon caused by ultrasound can only occur in the area near the probe. However, the non-contact ultrasonic cell disruptor installs the ultrasonic generator at the bottom of the water tank, so that the entire water tank is within the range of ultrasound, and the ultrasonic effect is widely and evenly distributed, reducing the formation of foam. During the experiment, the automatic continuous rotation of the independent sealed centrifuge tubes by the non-contact ultrasonic cell disruptor makes the distribution of ultrasonic energy more uniform. In the experimental process, the samples are placed in separate fully sealed centrifuge tubes, and there is no cross-contamination between samples, avoiding the spread of aerosols.


Advantages:
Traditional probe-type ultrasonic cell disruptors come into direct contact with the sample, leading to metal ion contamination, and can only handle one sample at a time with a long experimental cycle. For multiple samples, the same probe needs to be reused, which can easily cause cross-contamination between samples. Moreover, since the depth of each probe insertion is different, the distribution of ultrasonic energy during each use is also different, affecting the repeatability and accuracy of experimental results. In addition, since a closed system cannot be used, the aerosols or foams generated during ultrasonic processing will spread into the environment, posing a potential biological hazard. The non-contact ultrasonic cell disruptor can simultaneously process 4-32 samples, with high experimental efficiency; there is no need to frequently operate the probe, and each sample is in a separate fully enclosed test tube, avoiding cross-contamination. With a 4°C water bath, the ultrasonic energy is evenly distributed and the ultrasonic effect is complete. The ultrasonic parameters are flexible, and the experimental steps are standardized, with good experimental repeatability and high reliability of results.


Product Features
⒈ No aerosol or floating particles produced - enhanced biological safety (e.g. branched bacteria, viruses, etc.)
⒉ Closed ultrasonic processing eliminates the risk of sample cross-contamination
⒊ Eliminates the traditional problem of probe wear and tear
⒋ Can process a variety of samples, with a wide range of sample processing options
⒌ Suitable for a variety of standard containers
⒍ Can be used for processing small samples, as small as 5ul, with multiple sample adapters available from 0.2 to 1000ml
⒎ Automatic continuous rotation of centrifuge tubes driven by the motor makes the energy distribution of ultrasound more uniform, and the tubes are rotated at a low speed to ensure consistency of sample shearing
⒏ Built-in cooling water motor eliminates the worry of cooling water overflow


Application Range
⒈Fragmentation of DNA samples for second-generation sequencing
⒉Fragmentation of RNA samples
⒊Lysis of bacteria and cells
⒋ChIp assay (chromatin immunoprecipitation)
⒌Sample pre-processing for high-throughput sequencers
⒍Extraction of histones/proteins
⒎Homogenization and emulsification reactions
⒏Ultrasound treatment of valuable reagents
⒐Immunoprecipitation experiments/catalytic reactions


Technical Specifications    
Model: LAWSON21-1200 LAWSON21-2200
Power: 15-1500W continuously adjustable 30-3000W continuously adjustable
Standard sample processing volume: 20 holes * 5ml, 15 holes * 10-15ml, and 1 hole * 500-1000ml flask 30 holes * 0.1ml, 20 holes * 5ml, 15 holes * 10-15ml, and 1 hole * 500-1000ml flask
Optional sample processing volume: 99 holes * 0.2ml, 9 holes * 0.5ml, 32 holes * 1.5ml 99 holes * 0.2ml, 9 holes * 0.5ml, 32 holes * 1.5ml
Single ultrasound time: 0.1-99.9S 0.1-99.9S
Single gap time: 0.1-99.9S 0.1-99.9S
Total time (ultrasound + gap): 1-99H59M59S 1-99H59M59S
Frequency range: 21KHz (20-40KHz customizable) 21KHz (20-40KHz customizable)
Cooling system - temperature control range: Portable constant temperature bath mainframe (compressor refrigeration) -5 ~ 100℃ (optional) Portable constant temperature bath mainframe (compressor refrigeration) -5 ~ 100℃ (optional)
Temperature reading accuracy: ±0.1 ℃ ±0.1 ℃
Compressor power: 800W 800W
Ultrasonic water bath volume: 3L (15.5*14*14cm) 3L (15.5*14*14cm)
Adapter material: 316 stainless steel material 316 stainless steel material
Dimensions: 33*50*39cm 33*50*39cm
Weight: 25kg 25kg
Noise level: <50dB <50dB
Imported original multi-frequency ultrasonic transducer 12 sets 22 sets
Power supply (optional 110V): 220V/110V/50Hz/60HZ 220V/110V/50Hz/60HZ


Important Notes
1. Choose an appropriate probe based on the sample volume being processed. A dedicated wrench is required for changing the probe;
2. When the AMPLITUDE knob is turned on, the probe should not be exposed to air. In special circumstances (testing the probe), it should not exceed 10 seconds;
3. Prepare an ice box before use. The sample must be placed in an ice bath during processing, and the sample concentration should not be too high.
Product List
LAWSON21-1200 Unit
Host Machine Unit
Adapters set
Special Cooling Equipment Set
Power cord piece
User manual copy
Warranty card copy
Certificate of qualification copy
Description
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Choose any one
Optional
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