• Non-contact Ultrasonic Processor
  • LAWSON08-II
  • LAWSON08-II
  • Non-contact Ultrasonic Processor
  • Standard configuration for single sample processing size is 1.5 or 2 mL*32 holes.
LAWSON08-III Non-contact Ultrasonic Processor is commonly used for sterile cell disruption. It can break chromosomes and disrupt cells through centrifuge tubes.
Product Introduction
LAWSON08-II non-contact ultrasonic cell disruptor is used for aseptic crushing, and can break chromosomes and crush cells through centrifuge tubes. It is suitable for ChP, ChP-seq, RNA-seq, chromatin shearing, and DNA shearing (for second-generation sequencing). It is specifically designed for pre-treatment of DNA samples for second-generation sequencing and chromatin immunoprecipitation experiments. Compared with traditional probe contact ultrasonic cell disruptors, non-contact samples can be crushed in a sealed container, without producing infectious aerosols. The ultrasonic probe does not contact the sample, avoiding cross-contamination. The non-contact ultrasonic cell disruptor can obtain quality, efficiency and safety that cannot be compared with traditional ultrasonic methods.
Multiple samples can be tested simultaneously, and the experimental efficiency is high. There is no wear or debris phenomenon. Each sample is in a separate fully enclosed test tube to avoid cross-contamination. An optional cooling water circulation system is available, which makes it easy to perform ultrasonic treatment in a 4℃ water bath, with even energy distribution and complete ultrasonic action. The ultrasonic parameters are flexible, the experimental steps are standardized, and the experimental repeatability is good, and the results are reliable.
It has gradually become an indispensable standardized tool for ChIP (chromatin immunoprecipitation) and DNA shearing research platforms. It has high experimental efficiency, reliable results, and good repeatability. It can handle samples as low as 5ul and is suitable for precious samples.


Working Principle:
TNon-contact Ultrasonic Processor (ultrasonic Processor) adopts a design with an ultrasonic generator installed at the bottom of the water tank. Traditional probe-type ultrasonic disrupters can only produce microfluidic phenomena near the probe, while the non-contact ultrasonic cell crusher, with the ultrasonic generator installed at the bottom of the water tank, puts the entire water tank within the range of ultrasonic waves. The ultrasonic action is widely and evenly distributed, reducing foam formation. During the experiment, the automatic continuous rotation of the centrifuge tube by the non-contact ultrasonic cell crusher makes the energy distribution of ultrasonic waves more even. In the experimental process, the samples are placed in separate fully sealed centrifuge tubes, and there is no cross-contamination between the samples, avoiding the spread of aerosols.


Advantages:
Traditional probe-type ultrasonic cell crushers have direct contact between the probe and the sample, which can cause contamination by metal ions. Only one sample can be processed at a time, and the experiment cycle is long. For multiple samples, the same probe needs to be reused, which can easily cause cross-contamination between samples. Moreover, since the depth of insertion of the probe into the sample and the distribution of energy of each ultrasound is not consistent, it can affect the reproducibility and accuracy of experimental results. In addition, as a closed system cannot be used, aerosols or foams generated during ultrasonic treatment may spread into the environment, causing potential biohazards. The non-contact ultrasonic cell crusher can simultaneously process 4-32 samples at a time, with high experimental efficiency. There is no need to frequently operate the probe, and each sample is placed in a separate fully enclosed test tube to avoid cross-contamination. The ultrasonic energy is evenly distributed using a 4-degree water bath, and the ultrasonic action is complete. The ultrasonic parameters are flexible, and the experimental steps are standardized, with good experimental reproducibility and high reliability of results.


Product Features
1. No aerosol and floating particles generated - enhanced biosafety (e.g. for branching bacteria, viruses, etc.)
2. Eliminates the risk of sample cross-contamination
3. Eliminates the traditional problem of probe wear and debris generation
4. Capable of handling a variety of samples with a wide range of sample processing
5. Suitable for a variety of standard containers
6. Can be used for processing small volume samples, as small as 5ul
7. Automatic continuous rotation of centrifuge tubes makes the distribution of ultrasonic energy more uniform
8. Optional high and low temperature constant temperature water bath, customized rotating base for Eppendorf tubes with various diameters according to customer needs


Application Range
⒈DNA fragmentation of second-generation sequencing samples
⒉RNA fragmentation
⒊Bacterial and cell lysis
⒋ChIP assay (Chromatin Immunoprecipitation)
⒌Sample pre-processing for high-throughput sequencers
⒍Extraction of membrane proteins and proteins
⒎Homogenization and emulsification reactions
⒏Ultrasonic treatment of valuable reagents


Product Advantages
The closed system prevents potential biological hazards from the diffusion of aerosols or foams generated during ultrasonic processing. The non-contact fully automatic ultrasonic cell disruptor can simultaneously detect 4-32 samples at a time, with high experimental efficiency. There is no need to frequently manipulate the probe, as each sample is in a separate fully enclosed test tube, avoiding cross-contamination. The distribution of ultrasonic energy is even, and the ultrasonic action is complete. The ultrasonic parameters are flexible, and the experimental steps are standardized, with good experimental repeatability and high result reliability.
【1】Large LCD screen display, optional 7-inch touchscreen control.
【2】Simultaneously detect 4 to 32 samples at a time, with high experimental efficiency.
【3】Closed system, avoiding cross-contamination and high safety.
【4】Multiple sample processing, with a wide range of applications.
【5】Effective in preventing sample foaming.
【6】Optional cooling water circulation device interface, compatible with low-temperature cooling fluid circulation machine.
【7】Optional RS485 or RS232 communication interface.


Technical Specifications    
Model: LAWSON08-I LAWSON08-II
Power: 2200W power auto-adjustment 3200W power auto-adjustment
Standard sample capacity per processing: 1.5 or 2ml * 16 holes 1.5 or 2ml * 32 holes
Optional adapter specifications: 0.5ml * 18 or 5ml * 18 holes, 15ml * 15 holes, or 50ml * 5 holes 0.5ml * 48 or 5ml * 18 holes, 15ml * 15 holes, 50ml * 5 holes, or 250ml * 1 hole
Display: True-color 4.3-inch capacitive touch screen display True-color 4.3-inch capacitive touch screen display
Single ultrasonic time: 0.1-99.9S 0.1-99.9S
Single gap time: 0.1-99.9S 0.1-99.9S
Total time (ultrasonic + gap): 1-99H59M59S 1-99H59M59S
Frequency range: 19.5-20.5KHz 19.5-20.5KHz
Temperature control range: 0-100 degrees (optional low-temperature constant temperature) 0-100 degrees (optional low-temperature constant temperature)
Alarm function: Temperature, time, overload, no-load, over-temperature Temperature, time, overload, no-load, over-temperature
Ultrasonic probe: Φ60(mm) Φ70(mm)
Ice bath function: Supported Supported
Data storage: 20 sets 20 sets
Instrument size (depth*width*height): 410*225*290(mm) 410*225*290(mm)
Net weight of ultrasonic host: 7kg 7kg
Gross weight of ultrasonic host: 10kg 10kg
Main machine external packaging (length*width*height): 470*305*430(mm) 470*305*430(mm)
Gross weight of sample processing room: 19kg 19kg
Processing room external packaging (length*width*height): 510*420*470(mm) 510*420*470(mm)
Optional Features: Computer communication + data printing Computer communication + data printing
Control Method: Single-chip microcomputer + TFT touch screen Single-chip microcomputer + TFT touch screen
Voice Alarm and Prompt Function: Available Available
Continuous Ultrasonic Function: Supported Supported
Power Supply (Optional 110V): 220V/110V/50Hz/60Hz 220V/110V/50Hz/60Hz


Notes
1. Select the appropriate probe according to the volume of the sample being processed. When changing the probe, use the dedicated wrench to tighten it.
2. When the AMPLITUDE knob is turned on, the probe should not be exposed to air. In special situations (testing the probe), it should not exceed 10 seconds.
3. Prepare an ice box before use. During sample processing, it must be placed in an ice bath, and the sample concentration should not be too high.
 
 


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LAWSON08-II Unit
Host Machine Unit
Adapters set
Special Cooling Equipment Set
Power cord piece
User manual copy
Warranty card copy
Certificate of qualification copy
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